A head injury is any trauma that leads to injury of the scalp, skull, or brain. The injuries can range from minor to serious brain injury and can be caused by a range of factors including impact to the head known as closed or open head injury, asphyxia, stroke or other neurotoxic affect.

Symptoms of brain injury are generally associated with loss of consciousness, amnesia and concussion or post-concussive symptoms. Concussion can include nausea, dizziness, vomiting, unequal pupils, confused mental state or varying levels of consciousness, seizure-like activity, and weakness on one side of the body or the inability to wake up (coma). Other symptoms may include excessive sleepiness, seizures, paralysis, speech and language problems, inattention, difficulty concentrating, impaired memory, faulty judgment, depression, irritability, changes in personality, severe head ache, emotional outbursts, disturbed sleep, diminished libido, difficulty switching between two tasks, and slowed thinking.

More gross physical disturbances can be observed on imaging scans such as MRI or CT. However, radiological studies such as MRI and CAT are not always sensitive to the detection of diffuse organic cerebral damage such as shearing type injuries and reliance on such can result in misdiagnosis of organic brain damage (Duncan et al., 2005; Gaetz & Bernstein, 2001; Gaetz & Weinberg, 2000; Gaetz, 2002; Garnett et al., 2000; Hoffman et al., 1995; Inglese et al., 2005; Thatcher et al., 1989; 1998).

Generally, improvements in neuropsychological and psychophysiological function are only seen in the first 12 months post brain injury (Dikmen et al., 1990; Lannoo et al., 2001; Millis et al., 2001) . However, despite the majority of patients reaching full recovery within 12 months, mild head injury is not always a mild experience (Bernstein, 1999; Hofman et al., 2002; Iverson, 2005) , and axonal injury is common feature of mild, moderate, and severe head injury (Fitzpatrick et al., 1998; Maxwell et al., 1997). The process of axonal injury is not necessarily immediate and can be delayed for up to 24 hours (Fitzpatrick et al., 1998; Maxwell et al., 1997; Povlishock, 1992).

The severity of one's injury does not always predict the actual severity and long lasting affect of the damage. Post-accident medical measures do not always predict the short and long term outcome of significant neuropsychological impairment, and this can be attributed to substantial organic factors, as opposed to a purely psychiatric basis (Binder, 1997; Gaetz & Weinberg, 2000; Iverson et al., 2000; King, 1996; Lovell et al., 1999) . Studies show that the clinical outcome of mild brain injury is frequently worse than might be predicted using conventional imaging methods, and patients can show long-term and severe disability (Barth et al., 1983; Binder, 1986; Deb et al., 1998; Gaetz & Weinberg, 2000; King, 1996; King, 2003).

Therefore, individuals who have suffered head injury are encouraged to obtain a thorough assessment as that which is provided by brain profiling.

When cognitive deficits are noted up to 5 years after injury they are more likely to be seen in the areas of memory functioning, attention, and processing speed (Deshpande et al., 1996; Millis et al., 2001; Ponsford et al., 1995; Tate et al., 1991) , in addition to marked impairment of reasoning and problem solving skills, even 5 years after injury (Deshpande et al., 1996; Millis et al., 2001) . As a result, many patients do not return to their premorbid level of functioning and are at increased risk for disabling and permanent impairment (Dikmen et al., 2003), and often permanent loss of employability (Ponsford et al., 1995) .

In addition to providing a comprehensive assessment of traumatic brain injury, Brain Profiling can also recommend appropriate treatment and therapies that go beyond that which is provided by traditional medical and rehabilitation teams.

next Read and find out more about our treatment options for brain injury .
next Read about our personalized medicine approach for brain injury.
next Read some of our case examples on brain injury.
next Look at some of our scientific publications on brain injury.

References

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Bernstein, DM (1999). Recovery from mild head injury. Brain Injury , 13 (3), 151-172.

Binder, LM (1986). Persisting symptoms after mild head injury: a review of the postconcussive syndrome. Journal of Clinical & Experimental Neuropsychology , 8 (4), 323-346.

Binder, LM (1997). A review of mild head trauma. Part II: Clinical implications. Journal of Clinical & Experimental Neuropsychology: Official Journal of the International Neuropsychological Society , 19 (3), 432-457.

Deb, S, Lyons, I, and Koutzoukis, C (1998). Neuropsychiatric sequelae one year after a minor head injury. Journal of Neurology, Neurosurgery, and Psychiatry , 65 (6), 899-902.

Deshpande, SA, Millis, SR, Reeder, KP, Fuerst, D, and Ricker, JH (1996). Verbal learning subtypes in traumatic brain injury: a replication. Journal of Clinical & Experimental Neuropsychology , 18 (6), 836-842.

Dikmen, S, Machamer, J, Temkin, N, and McLean, A (1990). Neuropsychological recovery in patients with moderate to severe head injury: 2 year follow-up. Journal of Clinical & Experimental Neuropsychology , 12 (4), 507-519.

Dikmen, SS, Machamer, JE, Powell, JM, and Temkin, NR (2003). Outcome 3 to 5 years after moderate to severe traumatic brain injury. Archives of Physical Medicine and Rehabilitation , 84 (10), 1449-1457.

Duncan, CC, Kosmidis, MH, and Mirsky, AF (2005). Closed head injury-related information processing deficits: An event-related potential analysis. International Journal of Psychophysiology , 58 (2-3), 133-157.

Fitzpatrick, MO, Maxwell, WL, and Graham, DI (1998). The role of the axolemma in the initiation of traumatically induced axonal injury. Journal of Neurology, Neurosurgery & Psychiatry , 64 (3), 285-287.

Gaetz, M and Bernstein, DM (2001). The current status of electrophysiologic procedures for the assessment of mild traumatic brain injury. Journal of Head Trauma Rehabilitation , 16 (4), 386-405.

Gaetz, M and Weinberg, H (2000). Electrophysiological indices of persistent post-concussion symptoms. Brain Injury , 14 (9), 815-832.

Gaetz, M (2002). An emerging role for event-related potentials in the assessment of brain injury. Clinical Neurophysiology , 113 (11), 1665-1666.

Garnett, MR, Blamire, AM, Rajagopalan, B, Styles, P, and Cadoux-Hudson, TAD (2000). Evidence for cellular damage in normal-appearing white matter correlates with injury severity in patients following traumatic brain injury: A magnetic resonance spectroscopy study. Brain , 123 (7), 1403-1409.

Hoffman, DA, Stockdale, S, Hicks, LL, and Schwaninger, JE (1995). Diagnosis and treatment of head injury. Journal of Neurotherapy , 1 (1), 14-21.

Hofman, PA, Verhey, FR, Wilmink, JT, Rozendaal, N, and Jolles, J (2002). Brain lesions in patients visiting a memory clinic with postconcussional sequelae after mild to moderate brain injury. Journal of Neuropsychiatry & Clinical Neurosciences , 14 (2), 176-184.

Inglese, M, Makani, S, Johnson, G, Cohen, BA, Silver, JA, Gonen, O, and Grossman, RI (2005). Diffuse axonal injury in mild traumatic brain injury: a diffusion tensor imaging study. Journal of Neurosurgery , 103 (2), 298-303.

Iverson, GL (2005). Outcome from mild traumatic brain injury. Current Opinion in Psychiatry , 18 (3), 301-317.

Iverson, GL, Lovell, MR, and Smith, SS (2000). Does Brief Loss of Consciousness Affect Cognitive Functioning After Mild Head Injury? Archives of Clinical Neuropsychology , 15 (7), 643-648.

King, NS (1996). Emotional, neuropsychological, and organic factors: their use in the prediction of persisting postconcussion symptoms after moderate and mild head injuries. Journal of Neurology, Neurosurgery & Psychiatry , 61 (1), 75-81.

King, NS (2003). Post-concussion syndrome: clarity amid the controversy? British Journal of Psychiatry , 183 (Oct), 276-278.

Lannoo, E, Colardyn, F, Jannes, C, and de Soete, G (2001). Course of neuropsychological recovery from moderate-to-severe head injury: a 2-year follow-up. Brain Injury 15(1):1-13 .

Lovell, MR, Iverson, GL, Collins, MW, McKeag, D, and Maroon, JC (1999). Does loss of consciousness predict neuropsychological decrements after concussion? Clinical Journal of Sport Medicine , 9 (4), 193-198.

Maxwell, WL, Povlishock, JT, and Graham, DL (1997). A mechanistic analysis of nondisruptive axonal injury: a review. Journal of Neurotrauma , 14 (7), 419-440.

Millis, SR, Rosenthal, M, Novack, TA, Sherer, M, Nick, TG, Kreutzer, JS, High, WM, Jr., and Ricker, JH (2001). Long-term neuropsychological outcome after traumatic brain injury. Journal of Head Trauma Rehabilitation , 16 (4), 343-355.

Ponsford, JL, Olver, JH, and Curran, C (1995). A profile of outcome: 2 years after traumatic brain injury. Brain Injury , 9 (1), 1-10.

Povlishock, JT (1992). Traumatically induced axonal injury: pathogenesis and pathobiological implications. Brain Pathology , 2 (1), 1-12.

Tate, RL, Fenelon, B, Manning, ML, and Hunter, M (1991). Patterns of neuropsychological impairment after severe blunt head injury. Journal of Nervous & Mental Disease , 179 (3), 117-126.

Thatcher, RW, Biver, C, McAlaster, R, Camacho, M, and Salazar, A (1998). Biophysical Linkage between MRI and EEG Amplitude in Closed Head Injury. NeuroImage , 7 (4), 352-367.

Thatcher, RW, Walker, RA, Gerson, I, and Geisler, FH (1989). EEG discriminant analyses of mild head trauma. Electroencephalography & Clinical Neurophysiology , 73 (2), 94-106.

 


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